首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   7794篇
  免费   721篇
  国内免费   309篇
耳鼻咽喉   37篇
儿科学   97篇
妇产科学   134篇
基础医学   668篇
口腔科学   232篇
临床医学   737篇
内科学   1492篇
皮肤病学   74篇
神经病学   366篇
特种医学   255篇
外国民族医学   2篇
外科学   590篇
综合类   1010篇
现状与发展   10篇
一般理论   3篇
预防医学   1736篇
眼科学   116篇
药学   412篇
  12篇
中国医学   252篇
肿瘤学   589篇
  2024年   16篇
  2023年   165篇
  2022年   243篇
  2021年   429篇
  2020年   461篇
  2019年   1018篇
  2018年   755篇
  2017年   478篇
  2016年   267篇
  2015年   347篇
  2014年   484篇
  2013年   757篇
  2012年   381篇
  2011年   444篇
  2010年   315篇
  2009年   378篇
  2008年   289篇
  2007年   224篇
  2006年   211篇
  2005年   162篇
  2004年   120篇
  2003年   112篇
  2002年   85篇
  2001年   74篇
  2000年   72篇
  1999年   70篇
  1998年   31篇
  1997年   25篇
  1996年   50篇
  1995年   86篇
  1994年   64篇
  1993年   22篇
  1992年   15篇
  1991年   16篇
  1990年   12篇
  1989年   16篇
  1988年   25篇
  1987年   17篇
  1986年   10篇
  1985年   23篇
  1984年   16篇
  1983年   13篇
  1982年   8篇
  1981年   9篇
  1980年   5篇
  1978年   1篇
  1974年   2篇
  1973年   1篇
排序方式: 共有8824条查询结果,搜索用时 15 毫秒
91.
目的筛选我国脊柱外科被引最高的50篇文献,分析其主要特征。方法利用中国生物医学期刊引文数据库,检索我国33本骨科主要期刊。根据被引频次排名,筛选脊柱外科被引最高的50篇文献,分析其主要信息。结果被引最高的50篇文献被引频次从391次到80次。发表于1994-2006年间。刊登于7本期刊,《中华骨科杂志》、《中国脊柱脊髓杂志》、《中华外科杂志》和《颈腰痛杂志》最多。分布于12个省市,北京最多。来源于24所机构,苏州大学一附院最多。8位第一作者发表一篇以上文献。脊柱退行性疾病相关文献最多。结论被引最高文献的总结有助于认识我国脊柱外科领域经典文献的主要特征,了解该领域发展历史并指导未来研究,为青年医师阅读提供参考。  相似文献   
92.
93.
China is geographically located in the east of Asia and its population exceeds 1.3 billion. An understanding of dental education in China is thus of interest. However, as there is little published information on this topic, this paper provides information about China regarding its dental history, dental school system including curriculum and dental licensure. High school graduates take a nationwide entrance examination to apply for dental school, of which there are more than 50 in China. A five year dental education leads to the BDS degree. Dental school graduates must then pass the nationwide licensure examination to practise dentistry. Currently, there are not adequate numbers of dentists to provide the necessary oral health care for people living outside metropolitan areas.  相似文献   
94.
Objective This study was aimed at examining the trends and correlates of physical activity (PA) and sedentary behaviors among Chinese children. Methods A total of 4,341 subjects (6,936 observations) aged 6–17 years who participated in the China Health and Nutrition Survey (2004–2015) were included. Of the subjects, 41% participated in the survey twice or more. Random-effects ordinal regression models and repeated-measures mixed-effects models were used to examine the PA trends. Quantile regression models were applied to examine the factors influencing PA and sedentary behaviors. Results From 2004 to 2015, the prevalence of physical inactivity among Chinese children aged 6–17 years increased by 5.5% [odds ratio (OR), 1.51; 95% confidence interval (CI), 1.19–1.90; P < 0.001]. The PA volume declined by 5.8 metabolic equivalent of task-hr/week (P < 0.001), and the time spent in sedentary behaviors increased by 1.8 hr/week (P < 0.001). Age, ethnicity, and region showed significant effects on the PA volume across the quartiles (P < 0.001). Across the quartiles, sedentary time was significantly higher in the children residing in urban areas (P < 0.001) or areas with high urbanization levels (P ≤ 0.005) than in their counterparts. Conclusions A declining PA trend among Chinese children aged 6–17 years was observed from 2004 to 2015, and certain subgroups and geographical areas are at higher risk of physical inactivity.  相似文献   
95.
目的探索"华西项目化工作模式"在新型冠状病毒(2019-nCoV)疫情在线防控工作中的应用价值。方法基于四川大学华西医院丰富的抗震救灾和项目管理经验,依托PDCA循环持续优化"华西项目化工作模式"。结果"华西项目化工作模式"可运用于新型冠状病毒(2019-nCoV)突发公共卫生事件,已建立快速反应工作闭环,整个项目组运行良好、系统运维稳定。结论"华西项目化工作模式"为疫情在线防控工作提供了工作路径,采用互联网+方式远程协作办公方式,有效促进疫情应急管理科学化,在疫情在线干预防控工作中起到了积极作用。  相似文献   
96.
尿控是泌尿外科学的重要分支学科,也是最为复杂的领域之一。我国尿控领域的科研与临床工作起步较晚、起点较低。近40年来,在全国泌尿界同仁的共同努力下,我国尿控领域在尿动力学、尿失禁、膀胱过度活动症、神经泌尿学、功能泌尿学、盆底功能障碍等领域有了飞速发展,取得了显著进步,但与国际水平相比仍存在一定差距。《中华泌尿外科杂志》一直伴随着中国尿控事业的发展,正值她创刊40周年之际,我们以检索到的杂志发表论文为循证依据展开综述,系统回顾我国尿控事业的发展历程,展示学科建设成果,以兹祝贺《中华泌尿外科杂志》40岁生日,并鞭策激励我国尿控工作者更加努力,共同推动我国尿控事业向更高水平发展。  相似文献   
97.
From 2010, porcine epidemic diarrhea virus (PEDV) variants caused sequential outbreaks of disease in Asia and the United States. In this retrospective study, 49 complete spike (S) gene sequences were obtained from PEDV strains collected in China from 2014 to 2016. We observed that variant PEDV strains with novel insertions, deletions, and multiple S gene recombination types were present in China. In addition, mixed infections involving different variant strains were observed in some areas. Based on phylogenetic and recombination analyses, we determined that the newly emerged PEDV variants potentially originated via recombination between the earliest Chinese G1 genogroup strain, JS‐2004‐2 and earlier Korean pandemic strains. These findings provide important information for understanding ongoing PEDV outbreaks and suggest that novel variants make it more difficult to prevent PEDV infection.  相似文献   
98.

Background/Purpose

Only limited information is available about the detailed characteristics of qnrD, a plasmid-mediated quinolone resistance (PMQR) gene. This study aimed to understand the distribution of qnrD and the characterization of qnrD-carrying plasmids in Proteeae.

Methods

The distribution of qnrD genes was investigated by polymerase chain reaction (PCR) amplification in 203 consecutive nonduplicate clinical isolates of Proteeae collected from inpatients at the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. The minimum inhibitory concentrations (MICs) of antibiotics were measured by agar dilution method and other PMQR determinants were also determined by PCR. qnrD was positioned via Southern hybridization and the transferability of qnrD-carrying plasmids was achieved by conjugation experiment. The genetic environment of qnrD was investigated by sequencing, and chromosomal polymorphism for qnrD-positive strains was analyzed by pulsed-field gel electrophoresis (PFGE).

Results

Forty strains carried qnrD, showing decreased fluoroquinolone susceptibility or low-level fluoroquinolone resistance. qnrD was encoded on the plasmid of about 2.7 kb or 5.2 kb in length, which cannot be transferred by liquid conjugation or filter mating, but can be successfully transferred by transduction. The transformants showed 62.5–300-fold increases in the MICs of quinolones compared with the recipient. The plasmids carrying qnrD showed a high similarity with that of Providencia spp. and Proteus vulgaris. PFGE analysis demonstrated that these isolates were divergent and not clone related.

Conclusion

qnrD could have originated from Proteeae or presented in these bacteria as a reservoir; furthermore, qnrD could be transferred and spread within the same or across different bacterial species if the plasmids acquired mobile elements under antimicrobial selective pressures.  相似文献   
99.

Purpose

we studied the effect of Bacillus licheniformis preparation (ZCS) on CNST (central nervous system tumor) patients undergoing the gastrointestinal symptoms and inflammation induced by radiotherapy.

Materials and Methods

160 CNST patients with craniospinal irradiation (CSI) treatment were divided into experiment and control group. The experiment group patients took one capsule per time of ZCS and three times a day until the end of radiotherapy, starting one day before radiotherapy. While the patients in control group were administrated placebo without any probiotics. Serum from one day before radiotherapy and the first day after radiotherapy were collected to measure the ET, CRP, TNF-α, IL-1β and IL-6.

Results

More than 70% CNST pediatric patients suffered from different degrees of gastrointestinal symptoms after radiotherapy, including mouth ulcer, nausea, vomiting, abdominal pain and diarrhea. And there was an obviously increased of serum ET, TNF-α, IL-1β, IL-6 and CRP after RT. Importantly, a markedly decreased of ET, CRP and inflammatory cytokines were detected in the experiment group comparing to the control group after radiotherapy, as well as the relief of the gastrointestinal symptoms. However, improvement of probiotics (or ZCS) of the survival rate of CNST children and the recurrence of tumor are not observed in this study.

Conclusions

Prophylactically administrated ZCS during radiotherapy for CNST patients can relieve RT-related gastrointestinal symptoms and inflammatory reaction.  相似文献   
100.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号